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AG0035DM

698387-09-6 | (2E)-N-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

Chemical structure of (2E)-N-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide, CAS 698387-09-6
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CAS Number 698387-09-6
Catalog Number AG0035DM(AGN-PC-0TWZGN)
Chemical Name (2E)-N-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
IUPAC Name (E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
InChI InChI=1S/C30H29ClN6O3/c1-4-39-28-16-25-23(15-26(28)36-29(38)9-7-13-37(2)3)30(20(17-32)18-34-25)35-21-10-11-27(24(31)14-21)40-19-22-8-5-6-12-33-22/h5-12,14-16,18H,4,13,19H2,1-3H3,(H,34,35)(H,36,38)/b9-7+
InChI Key JWNPDZNEKVCWMY-VQHVLOKHSA-N
MDL Number MFCD09752958
Molecular Formula C30H29ClN6O3
Molecular Weight 557.0427
SMILES ClC=1C=C(C=CC1OCC1=NC=CC=C1)NC1=C(C=NC2=CC(=C(C=C12)NC(C=CCN(C)C)=O)OCC)C#N
UNII JJH94R3PWB
Synonyms
HKI 272, HKI-272, HKI272, N-(4-(3-chloro-4-(2-pyridinylmethoxy)anilino)-3-cyano-7-ethoxy-6-quinolyl)-4-(dimethylamino)-2-butenamide, neratinib, Neratinib, 698387-09-6, HKI-272, Neratinib (HKI-272), Nerlynx, HKI 272, Neratinib(HKI-272), UNII-JJH94R3PWB, PB-272, JJH94R3PWB, CHEMBL180022, WAY-179272, (2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide, (E)-N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide, C30H29ClN6O3, Q-101402, (2e)-n-(4-((3-chloro-4-((pyridin-2-yl)methoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide, (E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide, Neratinib [USAN:INN], AK170454, PB 272, Neratinib HKI 272, PubChem22399, Tube708, Neratinib (USAN/INN), Neratinib - HKI-272, cc-32, JSPY-st000262, SCHEMBL571762, SCHEMBL571763, BIFK0031, GTPL5686, CDP-820, DTXSID70220132, EX-A062, QCR-104, SYN1140, Neratinib(HKI-272)/HKI272, ZX-AFC000299, BCPP000151, AOB87125, ZINC3916214, ABP000871, AN-546, BDBM50161957, MFCD09752958, s2150, WAY-179272-B, AKOS005146340, AKOS025149637, BCP9000984, DB11828, RL04677, SB16595, NCGC00241101-01, NCGC00241101-03, AC-25073, AS-16279, BC256322, HY-32721, SC-28031, AB0008022, X2638, EC-000.2260, A25338, D08950, Z-3202, 387N096, I06-2375, BRD-K85606544-001-01-8, 698387-09-6, HKI272, HKI 272, HKI-272,, (2e)-n-(4-((3-chloro-4-((pyridin-2-yl)methoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide neratinib, (2E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide, (2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide;HKI-272, (E)-4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide, (E)-N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylami, (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide, 2-Butenamide, N-(4-((3-chloro-4-(2-pyridinylmethoxy)phenyl)amino)-3-cyano-7-ethoxy-6-quinolinyl)-4-(dimethylamino)-, (2E)-, 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide, N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide, Neratinib maleate, Neratinib [USAN], D0Q9CY, Neratinib (ERBB2 inhibitor), HKI272, ACN-039807, CID9915743, CS-0035, CID 9915743, A8322, A10638, C487932, N-(4-(3-Chloro-4-(2-pyridinylmethoxy)anilino)-3-cyano-7-ethoxy-6-quinolyl)-4-(dimethylamino)-2-butenamide, Neratinib, 99%, a highly selective HER2 and EGFR inhibitor - 10MG 10mg, (2E)-N-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide, -N-[4-[[3-chloro-4-[ methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4- but-2-enamide, N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)butanamide,

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    Conclusion: The above product meets the specifications of Angene.
    Analyst:Chase
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    Reviewed by:Jessie
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    Angene International Limited